Postdoctoral Associate in cryogenic electron microscopy (CryoEM)

 JOB
DESCRIPTION: 

Join a dynamic structural biology group, where we
push the boundaries of molecular visualization and membrane biology. Our lab
integrates cutting-edge cryoEM, membrane biophysics, and infection/immunity
research to redefine how receptors like integrins are regulated. This position
offers the opportunity to drive high-impact projects, publish in top journals,
and grow your expertise in method development and biological discovery. 

About this opportunity 

Successful candidates will work in a cutting-edge
research environment with new state-of-the-art facilities. The laboratory has
outstanding cell biology, molecular biology, protein expression, purification,
biochemistry, cryogenic electron microscopy, and protein crystallography
facilities. The laboratory has access to many exceptional Cores, facilitating
basic research and drug development. The unique infrastructure includes the
application of unique chemical, genomic, proteomic, informatics, and high-throughput
screening and engineering tools for discovering novel biomolecules. 

CryoEM at The Wertheim UF Scripps
Institute  

We installed the first 300 kV cryo Atomic Resolution
Microscope (cryoARM300) in the Americas (https://www.youtube.com/watch?v=xdVxAN8xy1w&feature=youtu.be) and
have plenty of microscope time dedicated to the post-doctoral associates. This
state-of-the-art transmission electron microscope is a 300 kV high-resolution
microscope capable of carrying out cryogenic electron microscopy studies by
providing atomic resolution for structural studies involving single particle
analyses. The transmission electron microscope is equipped with a new and
improved Gatan K3 direct electron detector camera with better DQE, a larger
field of view (24 Megapixels – 5,760 x 4,092), and faster (3.75 times that of
the K2 camera). The direct detection devices are exquisitely sensitive, produce
high signal-to-noise images, and are ideal for high-resolution studies. 

X-ray crystallography at The Wertheim UF
Scripps Institute  

The lab has access to SER-CAT beamlines at Sector 22
of the Advanced Photon Source, including modern insertion device lines
(22-ID-D, variable wavelength, and 22-ID-E, fixed wavelength) as well as a
bending magnet line (22-BM) for macromolecular crystallography. These
facilities are equipped with updated optics and detectors, and fall under
current APS upgrades, ensuring high performance for structural biology
projects. 

The lab has access to a HighFlux X-ray diffraction
system, specifically a Rigaku MicroMax-007 HF, a second-generation microfocus
rotating anode generator, and a mar345 Image Plate detector. An Osmic VariMax
optics system and the Proteros Free Mounting System can be used to control the
humidity and optimize diffraction characteristics, including resolution,
mosaicity, anisotropy, and reduced X-ray background. 

Intellectual environment 

The Wertheim UF Scripps Institute shares its Jupiter
campus with the Max Planck Florida Institute for Neuroscience (MPFI),
North America's only Max Planck Institute. MPFI is internationally recognized
for innovation in imaging and neuroscience, and its presence creates a unique,
highly collaborative research environment. Postdocs benefit from joint
seminars, shared facilities, interdisciplinary collaborations, and daily
interaction with world-class scientists across structural biology, chemical
biology, and neuroscience. This close partnership expands opportunities for
discovery and professional growth beyond what most academic campuses offer. 

Why Jupiter, Florida? 

The Wertheim UF Scripps Institute is located
in Jupiter, Florida, a vibrant coastal community in Palm Beach County.
Jupiter offers an outstanding quality of life with year-round sunshine,
beautiful beaches, outdoor recreation, and a safe, family-friendly atmosphere.
The area combines the advantages of a relaxed lifestyle with proximity to Miami
and Orlando for cultural and professional opportunities. Florida has no
state income tax, making post-doctoral salaries go further, and the cost of
living in northern Palm Beach County is favorable compared to many other
significant research hubs. The campus itself is part of a growing biotech
corridor that includes Max Planck Florida, providing an interdisciplinary,
collaborative environment with cutting-edge science in an exceptional
location. 

EXPECTED SALARY: 

NRSA Salary.  

MINIMUM
REQUIREMENTS: 

Applicants
with a recently awarded Ph.D. degree in structural biology are prioritized. 

PREFERRED
QUALIFICATIONS: 

• Experience in cryogenic electron
  microscopy (cryoEM). 
• Any structural biologist is highly
  encouraged to apply. 

SPECIAL
INSTRUCTIONS TO APPLIANTS:  

The
University of Florida is a member of the State University System of Florida and
an Equal Opportunity Employer. All qualified applicants will receive
consideration for employment based on merit.


If an accommodation due to a disability is needed to apply for this position,
please call 352-392-2477 or the Florida Relay System at 800-955-8771 (TDD) or
visit Accessibility at
UF.


In order to be considered, please upload a cover letter and resume.
 

For any
inquiries, you may contact Dr. T. Izard, at t.izard@ufl.edu 

The final
candidate will be required to provide official transcript to the hiring
department upon hire. A transcript will not be considered "official"
if a designation of "Issued to Student" is visible. Degrees earned
from an education institution outside of the United States are required to be
evaluated by a professional credentialing service provider approved by National
Association of Credential Evaluation Services (NACES), which can be found
at http://www.naces.org/. 

Please
provide names and email addresses of three to five references as part of the UF
application process. When ready, the hiring department will contact the listed
references via email requesting their reference letters to be uploaded directly
to the application website. 

This
position is open until filled. Applications will be reviewed on a regular
basis.  

This is a
time-limited position.  

To apply for this position, visit https://jobs.ufl.edu/
Job number for this vacancy is 521437 and the deadline date to apply is open
until filled. If an accommodation due to a disability is needed to apply for
this position, please call (352) 392-2HRS or the Florida Relay System at (800)
955-8771 (TDD). 

The University of Florida is an
equal Opportunity Employer dedicated to building a broadly diverse and
inclusive faculty and staff. The University of Florida invites all qualified
applicants, including minorities, women, veterans, and individuals with
disabilities. The University of Florida is a public institution and subject to
all requirements under the Florida Sunshine and Public Records laws. 

REQ # 539186